Mouse anti-Human IgM Antibody

Catalog No. ABIN969482

Quick Overview for Mouse anti-Human IgM Antibody (ABIN969482)

Target: IgM

Clonality: Monoclonal

Application: ELISA

Clone: 3H10G5F2

Isotype: IgG1

Product Details

Reactivity: Human

Host: Mouse

Purpose: human IgM Antibody

Purification: Purified antibody

Immunogen: ChromPure Human IgM (myeloma), whole molecule.

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Monoclonal antibodies should not be stored at a temperature below -25 °C due to the aggregation effect of the protein.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References

Klonisch, Panayotou, Edwards, Jackson, Berger, Delves, Lund, Roitt: "Enhancement in antigen binding by a combination of synergy and antibody capture." in: Immunology, Vol. 89, Issue 2, pp. 165-71, (1996) (PubMed).

Target Details

Target: IgM

Target Type: Antibody

Background: Immunoglobulin M (IgM), along with IgA, IgD, and IgE, make up approximately 20 % of the total gamma globulin in the body, with IgG accounting for the other 80 %.Each class of antibody gets its designation from the heavy and light peptide chains that make up the antibody structure.IgM is the first immunoglobulin produced during the immune response and the first antibody produced in neonates. Serum levels of IgM are associated with certain autoimmune diseases, and abnormally low levels may indicate the presence of Wiskott-Aldrich Syndrome, an inherited immunodeficiency disorder. Monoclonal Anti-Human IgM is derived from the hybridoma1 produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.